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VW's Computer Cheat Code Found By Researchers

carscoops.com

VW's Computer Cheat Code Found By Researchers

- Following a year-long investigation, an international team of researchers found the code which had previously allowed VW to "cheat" U.S and European emissions tests. The research team, led by Kirill Levchenko, a computer scientist at the University of California San Diego, will present these findings at the 38th IEEE Symposium on Security and Privacy in the San Francisco Bay Area, from May 22nd to May 24th

Categories: Science & Nature |  Motoring | 
Places: United States |  West |  Pacific |  California | 

WSU researchers need volunteers to smoke marijuna for study

kgw.com

WSU researchers need volunteers to smoke marijuna for study

- PULLMAN, Wash. – Washington State University researchers are in need of volunteers for a study to develop a breathalyzer that detects marijuana use. Under Washington law, drivers with five nanograms of active tetrahydrocannabinol, also referred to as THC, in their bloodstream can be prosecuted for driving under the influence. Research Assistant and City Councilor Nathan Weller said the research team felt there was a tremendous need for quick-response detection technology

Categories: Science & Nature | 
Places: Americas |  North America |  United States |  West |  Pacific |  Washington |  Whitman |  Pullman | 

Climate Change Caused By The Penis, According To Academic Journal

inquisitr.com

Climate Change Caused By The Penis, According To Academic Journal

- Two Ph.Ds say that hoaxed a peer-reviewed academic journal into publishing a paper that, among other things, claimed that the “conceptual penis” is driving climate change and that hypermasculinity is irreparably damaging the ecosystem. The authors claim they purposely loaded up the paper, “The conceptual penis as a social construct,” with lofty academic gibberish and fake sources that seemed to validate what they suggest is a prevailing, anti-male gender studies philosophy

Categories: Science & Nature | 
Places: Americas |  North America |  United States | 

The United States must act quickly to control the use of e-cigarettes

nature.com

The United States must act quickly to control the use of e-cigarettes

- In the time it takes you to read this article, at least one cigarette smoker in the United Kingdom will have switched to vaping. As economic uncertainty grips many industries, the use of e-cigarettes is booming. The £6.1-billion (US$7.9-billion) global market for them is now about 20 times what it was in 2010. It is expected to double again in the next three years

Categories: Science & Nature |  Travel & Recreation | 
Places: Americas |  North America |  United States | 

Berkeley Pit water leads to scientific discovery

billingsgazette.com

Berkeley Pit water leads to scientific discovery

- BUTTE — Organisms found in the Berkeley Pit's toxic water are leading to a scientific breakthrough, according to two University of Montana professors who are former Butte residents. Andrea and Don Stierle paired together two fungi taken from pit water in Butte. That pair produced a compound that has the ability to fight drug-resistant bacteria in a laboratory setting. The Stierles' new findings are published in a paper that appeared in The Journal of Natural Products last month

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Berkeley Pit water leads to scientific discovery

missoulian.com

Berkeley Pit water leads to scientific discovery

- BUTTE — Organisms found in the Berkeley Pit's toxic water are leading to a scientific breakthrough, according to two University of Montana professors who are former Butte residents. Andrea and Don Stierle paired together two fungi taken from pit water in Butte. That pair produced a compound that has the ability to fight drug-resistant bacteria in a laboratory setting. The Stierles' new findings are published in a paper that appeared in The Journal of Natural Products last month

Categories: Science & Nature | 
Places: Americas |  North America |  United States |  West |  Mountain |  Montana |  Pacific |  California |  North |  Sierra Nevada |  Butte | 

Found: A Neptune-sized planet with sulfur-rich clouds and a watery atmosphere

latimes.com

Found: A Neptune-sized planet with sulfur-rich clouds and a watery atmosphere

- Scientists peering at a “warm Neptune” roughly 430 light-years away have discovered far less water in the gassy planet’s atmosphere than they expected — which puts it at odds with the ice giants in our own solar system. The atmosphere of HAT-P-26b, described in the journal Science, runs counter to some long-standing theories about planetary development and could help scientists understand the diversity of worlds beyond our own

Categories: Science & Nature | 
Places: Americas |  North America |  United States | 

Secretary of Energy Rick Perry visits Idaho National Laboratory

eastidahonews.com

Secretary of Energy Rick Perry visits Idaho National Laboratory

- We Matched IDAHO FALLS — Rick Perry made his first trip to the Gem State as the 14th U.S. Secretary of Energy on Monday and Tuesday. The former Texas governor spent the two days touring parts of the Idaho National Laboratory and the Naval Reactors Facility. He was accompanied by U.S. Congressman Mike Simpson, R-Idaho, and Naval Nuclear Propulsion Program Admiral James F

Categories: Politics & Government |  Science & Nature | 
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Danger below — R.I.'s network of gas pipes is leaky

providencejournal.com

Danger below — R.I.'s network of gas pipes is leaky

- This Journal Special Report examines the integrity of Rhode Island's gas lines, one of the oldest networks in the country, with roots that stretch back before the Civil War. Alex Kuffner Journal Staff Writer kuffneralex Rhode Island's natural gas distribution system has a troubling percentage of bare steel and iron pipes — outdated materials prone to corrosion and cracking that need to be replaced for the public's safety

Categories: Science & Nature | 
Places: Americas |  North America |  United States |  Northeast |  New England |  Rhode Island | 

Port: Kevin Cramer introduces bill to name Fargo research center after former Gov. Ed Schafer

inforum.com

Port: Kevin Cramer introduces bill to name Fargo research center after former Gov. Ed Schafer

- Last week North Dakota Congressman Kevin Cramer introduced a bill in Congress – HR2154 – which would rename the USDA’s Red River Valley Agricultural Research Center after former North Dakota Governor Ed Schafer.

Categories: Science & Nature |  Education | 
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Hartford Hospital Researchers Studying Pot Smoking And Driving

courant.com

Hartford Hospital Researchers Studying Pot Smoking And Driving

- — Pot-smoking volunteers are getting high at Hartford Hospital's Institute of Living these days courtesy of the federal government, and it's all part of scientific research into marijuana's impact on highway safety. One federally funded study now underway at the hospital's Olin Neuropsychiatry Research Center is looking at the ways cannabis affects the brains of people as they drive motor vehicles

Categories: Science & Nature |  Health | 
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Walking benefits the brain

thehindu.com

Walking benefits the brain

- Researchers at New Mexico Highlands University (NMHU), U.S. have found that the foot’s impact during walking sends pressure waves through the arteries that significantly modify and can increase the supply of blood to the brain. The NMHU research team and others previously found that the foot’s impact during running (4-5 G-forces) caused significant impact-related retrograde (backward-flowing) waves through the arteries that sync with the heart rate and stride rate to dynamically regulate blood circulation to the brain

Categories: Science & Nature | 
Places: United States |  India | 

Artifacts preserve Holocaust stories for future generations

wbrc.com

Artifacts preserve Holocaust stories for future generations

- By BRIAN WITTE Associated Press BOWIE, Md. (AP) - The small wicker doll chair was a modest toy, but it meant the world to Louise Lawrence-Israels. A gift for her second birthday, it was the only toy she possessed during the approximately three years she spent hiding from the Nazis in Amsterdam, just five blocks from the house where Anne Frank wrote in her diary

Categories: Science & Nature | 
Tags: Scientific Research | 
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Study: Diet soda may be linked to higher risk of stroke and dementia, more research needed

abc3340.com

Study: Diet soda may be linked to higher risk of stroke and dementia, more research needed

- COLUMBUS, Ohio (WSYX/WTTE) — A new study showed that diet soda may be linked to a higher risk of stroke and dementia. The study that was published in the American Heart Association's Journal looked at diet sodas and other artificially sweetened drinks. The study already has its critics though. Researchers that prepared the study have admitted they could not find an actual cause-an-effect relationship between the two

Categories: Science & Nature |  Health | 
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Federal cuts may inhibit future of Prudence Island research center

wpri.com

Federal cuts may inhibit future of Prudence Island research center

- Related Coverage For nearly two decades, the Narragansett Bay National Estuarine Research Reserve has collected information critical in the study and preservation of the bay and the organisms that live inside it. The future of the center is shrouded in uncertainty, however, as Congress reviews President Donald Trump’s proposed budget. Under Trump’s budget, $250 million for programs supporting coastal and marine management, research and education could be eliminated

Categories: Science & Nature | 
Tags: Scientific Research | 
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Cincinnati native hurt in pool party accident accepted into stem cell research study

wlwt.com

Cincinnati native hurt in pool party accident accepted into stem cell research study

- CINCINNATI — An Elder High School grad who was critically injured has been accepted into a stem cell research study at Rush University in Chicago, his family reported. Ryan Custer, a Wright State University freshman, He suffered a traumatic head injury, fracturing his vertebrae and sending him to the intensive care unit at the University of Cincinnati Medical Center. Family and friends said he's undergone multiple surgeries on his spine, was put on a breathing tube and has had a tracheotomy performed

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Places: Americas |  North America |  United States | 

UI expects to announce more on ag research center in May

magicvalley.com

UI expects to announce more on ag research center in May

- TWIN FALLS — Large-scale agricultural research is set to have a home in the Magic Valley. State lawmakers set aside the first $10 million to help fund a center here, but more fundraising is needed for the project to be realized. Educational institutions and industry groups will have to chip in two-thirds of the estimated $45 million needed to establish the center

Categories: Science & Nature | 
Tags: Scientific Research | 
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Latest Stories

VW's Computer Cheat Code Found By Researchers
VW's Computer Cheat Code Found By Researchers Following a year-long investigation, an international team of researchers found the code which had previously allowed VW to "cheat" U.S and European emissions tests. The research team, led by Kirill Levchenko, a computer scientist at the University of California San Diego, will present these findings at the 38th IEEE Symposium on Security and Privacy in the San Francisco Bay Area, from May 22nd to May 24th   Read More ...
Categories: Science & Nature |  Motoring | 
Places: United States |  West |  Pacific |  California | 
WSU researchers need volunteers to smoke marijuna for study
WSU researchers need volunteers to smoke marijuna for study PULLMAN, Wash. – Washington State University researchers are in need of volunteers for a study to develop a breathalyzer that detects marijuana use. Under Washington law, drivers with five nanograms of active tetrahydrocannabinol, also referred to as THC, in their bloodstream can be prosecuted for driving under the influence. Research Assistant and City Councilor Nathan Weller said the research team felt there was a tremendous need for quick-response detection technology   Read More ...
Categories: Science & Nature | 
Places: Americas |  North America |  United States |  West |  Pacific |  Washington |  Whitman |  Pullman | 
Some Social Scientists Are Tired of Asking for Permission
Some Social Scientists Are Tired of Asking for Permission If you took Psychology 101 in college, you probably had to enroll in an experiment to fulfill a course requirement or to get extra credit. Students are the usual subjects in social science research — made to play games, fill out questionnaires, look at pictures and otherwise provide data points for their professors’ investigations into human behavior, cognition and perception. But who gets to decide whether the experimental protocol — what subjects are asked to do and disclose — is appropriate and ethical? That question has been roiling the academic community since the Department of Health and Human Services’s Office for Human Research Protections revised its rules in January   Read More ...
Categories: Science & Nature |  Society & Culture | 
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Energy Secretary to tour Oak Ridge National Laboratory
NASHVILLE, Tenn. (AP) — U.S. Secretary of Energy Rick Perry is coming to Tennessee to tour the Oak Ridge National Laboratory. Department of Energy officials say Perry will tour the laboratory facilities with Sen. Lamar Alexander and Rep. Chuck Fleischmann on Monday. The Republican politicians had earlier this year stressed the value of Oak Ridge National Laboratory and invited him take a tour   Read More ...
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Pope tells geneticists that destroying embryos is unjustifiable
Pope tells geneticists that destroying embryos is unjustifiable VATICAN CITY Pope Francis praised scientists working on treatments for genetic diseases on Thursday but condemned any use of human embryos in medical research. "I encourage you to carry out (your work) in ways that do not contribute to nourishing the 'throwaway culture' that sometimes creeps into the world of scientific research," he said at an event aimed at raising awareness of Huntington's disease, a degenerative brain condition   Read More ...
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Places: Americas |  North America |  United States | 
Climate Change Caused By The Penis, According To Academic Journal
Climate Change Caused By The Penis, According To Academic Journal Two Ph.Ds say that hoaxed a peer-reviewed academic journal into publishing a paper that, among other things, claimed that the “conceptual penis” is driving climate change and that hypermasculinity is irreparably damaging the ecosystem. The authors claim they purposely loaded up the paper, “The conceptual penis as a social construct,” with lofty academic gibberish and fake sources that seemed to validate what they suggest is a prevailing, anti-male gender studies philosophy   Read More ...
Categories: Science & Nature | 
Places: Americas |  North America |  United States | 
South China Sea found to have heightened levels of anthropogenic surface nitrogen
South China Sea found to have heightened levels of anthropogenic surface nitrogen (Phys.org)—A team of researchers from Taiwan and the U.S. has found evidence of higher levels of anthropogenic surface nitrogen in the South China Sea, likely due to an increase in atmospheric nitrogen levels. In their paper published in the journal Science, the group describes their study of nitrogen deposition on coral reefs over the past half-century. Edward Boyle with MIT offers a Perspective piece on the work done by the team in the same issue along with an outline of nitrogen ocean processes   Read More ...
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Places: United States |  South | 
The United States must act quickly to control the use of e-cigarettes
The United States must act quickly to control the use of e-cigarettes In the time it takes you to read this article, at least one cigarette smoker in the United Kingdom will have switched to vaping. As economic uncertainty grips many industries, the use of e-cigarettes is booming. The £6.1-billion (US$7.9-billion) global market for them is now about 20 times what it was in 2010. It is expected to double again in the next three years   Read More ...
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Floor-plate-derived netrin-1 is dispensable for commissural axon guidance
Netrin-1 is an evolutionarily conserved, secreted extracellular matrix protein involved in axon guidance at the central nervous system midline. Netrin-1 is expressed by cells localized at the central nervous system midline, such as those of the floor plate in vertebrate embryos. Growth cone turning assays and three-dimensional gel diffusion assays have shown that netrin-1 can attract commissural axons. Loss-of-function experiments further demonstrated that commissural axon extension to the midline is severely impaired in the absence of netrin-1 (refs 3, 7, 8, 9)   Read More ...
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University spin-offs
A substantial proportion of researchers harbour entrepreneurial ambitions. In a survey of readers (), 47 of the 815 people who responded to the question said that they would consider leaving academia to commercialize their research in a start-up company. However, few ever actually do so — a mere 6 of the 1,403 respondents reported having started a company. The greatest perceived barriers were financial risk and insecurity (cited by 72 of respondents) and lack of business skills (53)   Read More ...
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Places: United States | 
Keep doors open for constructive dialogue between religion and science
Keep doors open for constructive dialogue between religion and science Dilia is the oldest of an unusual crowd of people due to meet Pope Francis this week at the Vatican. The 79-year-old widow from rural Colombia married into a family whose members carry the gene for Huntington’s disease, a hereditary neurodegenerative disorder. Fate was cruel. Of her 11 children, 9 inherited the disease. Five have died and the remaining four are sick   Read More ...
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Continental crust formation on early Earth controlled by intrusive magmatism
The global geodynamic regime of early Earth, which operated before the onset of plate tectonics, remains contentious. As geological and geochemical data suggest hotter Archean mantle temperature and more intense juvenile magmatism than in the present-day Earth, two crust–mantle interaction modes differing in melt eruption efficiency have been proposed: the Io-like heat-pipe tectonics regime dominated by volcanism and the “Plutonic squishy lid” tectonics regime governed by intrusive magmatism, which is thought to apply to the dynamics of Venus   Read More ...
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A rhodopsin in the brain functions in circadian photoentrainment in Drosophila
Animals partition their daily activity rhythms through their internal circadian clocks, which are synchronized by oscillating day–night cycles of light. The fruitfly Drosophila melanogaster senses day–night cycles in part through rhodopsin-dependent light reception in the compound eye and photoreceptor cells in the Hofbauer–Buchner eyelet. A more noteworthy light entrainment pathway is mediated by central pacemaker neurons in the brain. The Drosophila circadian clock is extremely sensitive to light   Read More ...
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Experimental characterization of a quantum many-body system via higher-order correlations
Quantum systems can be characterized by their correlations. Higher-order (larger than second order) correlations, and the ways in which they can be decomposed into correlations of lower order, provide important information about the system, its structure, its interactions and its complexity. The measurement of such correlation functions is therefore an essential tool for reading, verifying and characterizing quantum simulations. Although higher-order correlation functions are frequently used in theoretical calculations, so far mainly correlations up to second order have been studied experimentally   Read More ...
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Biology needs more staff scientists
Biology needs more staff scientists Most research institutions are essentially collections of independent laboratories, each run by principal investigators who head a team of trainees. This scheme has ancient roots and a track record of success. But it is not the only way to do science. Indeed, for much of modern biomedical research, the traditional organization has become limiting. A different model is thriving at the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, where I work   Read More ...
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Multidisciplinarity: Widen discipline span of Nature papers
Our informal analysis indicates that the biological sciences have dominated 's research content for more than 50 years. In an age that calls for greater multidisciplinarity, we suggest that the journal should include a broader range of high-impact papers from fields such as mathematics, chemistry and applied science. We searched Clarivate Analytics' Web of Science database for papers published in several different research fields during 1963–64, 2003–04 and 2013–14   Read More ...
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Work–life balance: Break or burn out
Work–life balance: Break or burn out Twice a week, postdoc Phil Auckland leaves the lab at 5:30 p.m. and drives an hour out of Coventry, UK, to a mountain-bike racing track and hills. Here, he finds diversion and distraction from his research programme in a cell-biology lab at the University of Warwick. “It requires so much focus and concentration, doing tricks and jumps, that you are not thinking about anything else,” he says   Read More ...
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A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma
The heterogeneity of cellular states in cancer has been linked to drug resistance, cancer progression and the presence of cancer cells with properties of normal tissue stem cells. Secreted Wnt signals maintain stem cells in various epithelial tissues, including in lung development and regeneration. Here we show that mouse and human lung adenocarcinomas display hierarchical features with two distinct subpopulations, one with high Wnt signalling activity and another forming a niche that provides the Wnt ligand   Read More ...
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Whole-brain serial-section electron microscopy in larval zebrafish
High-resolution serial-section electron microscopy (ssEM) makes it possible to investigate the dense meshwork of axons, dendrites, and synapses that form neuronal circuits. However, the imaging scale required to comprehensively reconstruct these structures is more than ten orders of magnitude smaller than the spatial extents occupied by networks of interconnected neurons, some of which span nearly the entire brain. Difficulties in generating and handling data for large volumes at nanoscale resolution have thus restricted vertebrate studies to fragments of circuits   Read More ...
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Topological defects control collective dynamics in neural progenitor cell cultures
Cultured stem cells have become a standard platform not only for regenerative medicine and developmental biology but also for biophysical studies. Yet, the characterization of cultured stem cells at the level of morphology and of the macroscopic patterns resulting from cell-to-cell interactions remains largely qualitative. Here we report on the collective dynamics of cultured murine neural progenitor cells (NPCs), which are multipotent stem cells that give rise to cells in the central nervous system   Read More ...
Categories: Science & Nature |  Health | 
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TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling
The mechanistic target of rapamycin (mTOR) has a key role in the integration of various physiological stimuli to regulate several cell growth and metabolic pathways. mTOR primarily functions as a catalytic subunit in two structurally related but functionally distinct multi-component kinase complexes, mTOR complex 1 (mTORC1) and mTORC2 (refs 1, 2). Dysregulation of mTOR signalling is associated with a variety of human diseases, including metabolic disorders and cancer   Read More ...
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Experimental evidence that thrust earthquake ruptures might open faults
Many of Earth’s great earthquakes occur on thrust faults. These earthquakes predominantly occur within subduction zones, such as the 2011 moment magnitude 9.0 eathquake in Tohoku-Oki, Japan, or along large collision zones, such as the 1999 moment magnitude 7.7 earthquake in Chi-Chi, Taiwan. Notably, these two earthquakes had a maximum slip that was very close to the surface. This contributed to the destructive tsunami that occurred during the Tohoku-Oki event and to the large amount of structural damage caused by the Chi-Chi event   Read More ...
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Places: United States | 
Global health: Boost multinational clinical research
Global cooperation in clinical research maximizes access to patients, enables resource sharing and increases the applicability of research findings. Yet academic trials are rarely multinational because they are beset with funding problems and variations in legal, regulatory and ethical requirements. The Clinical Research Initiative for Global Health (CRIGH) has taken up the challenge to overcome these. CRIGH is a worldwide partnership of research institutions and organizations that aims to establish a framework for international cooperation in non-commercial clinical trials and to promote evidence-based medicine (see www   Read More ...
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Places: Americas |  North America |  United States | 
Berkeley Pit water leads to scientific discovery
Berkeley Pit water leads to scientific discovery BUTTE — Organisms found in the Berkeley Pit's toxic water are leading to a scientific breakthrough, according to two University of Montana professors who are former Butte residents. Andrea and Don Stierle paired together two fungi taken from pit water in Butte. That pair produced a compound that has the ability to fight drug-resistant bacteria in a laboratory setting. The Stierles' new findings are published in a paper that appeared in The Journal of Natural Products last month   Read More ...
Categories: Science & Nature | 
Places: Americas |  North America |  United States |  West |  Mountain |  Montana |  Pacific |  California |  North |  Sierra Nevada |  Butte | 
Berkeley Pit water leads to scientific discovery
Berkeley Pit water leads to scientific discovery BUTTE — Organisms found in the Berkeley Pit's toxic water are leading to a scientific breakthrough, according to two University of Montana professors who are former Butte residents. Andrea and Don Stierle paired together two fungi taken from pit water in Butte. That pair produced a compound that has the ability to fight drug-resistant bacteria in a laboratory setting. The Stierles' new findings are published in a paper that appeared in The Journal of Natural Products last month   Read More ...
Categories: Science & Nature | 
Places: Americas |  North America |  United States |  West |  Mountain |  Montana |  Pacific |  California |  North |  Sierra Nevada |  Butte | 
Found: A Neptune-sized planet with sulfur-rich clouds and a watery atmosphere
Found: A Neptune-sized planet with sulfur-rich clouds and a watery atmosphere Scientists peering at a “warm Neptune” roughly 430 light-years away have discovered far less water in the gassy planet’s atmosphere than they expected — which puts it at odds with the ice giants in our own solar system. The atmosphere of HAT-P-26b, described in the journal Science, runs counter to some long-standing theories about planetary development and could help scientists understand the diversity of worlds beyond our own   Read More ...
Categories: Science & Nature | 
Places: Americas |  North America |  United States | 
HAARP enjoys new era of transparency and scientific research under UAF management
HAARP enjoys new era of transparency and scientific research under UAF management The High-Frequency Active Auroral Research Program (HAARP), a longtime favorite facility for conspiracy theorists, is enjoying a new era of transparency under the management of the University of Alaska Fairbanks. While the Air Force still owns the land on which the equipment sits, the military transferred responsibility for the facilities and equipment to UAF in   Read More ...
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Tags: Scientific Research | 
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A holey graphene electrode framework that enables highly efficient charge delivery
A holey graphene electrode framework that enables highly efficient charge delivery (Phys.org)—A team of researchers affiliated with institutions in the U.S., China and the Kingdom of Saudi Arabia has developed a new type of porous graphene electrode framework that is capable of highly efficient charge delivery. In their paper published in the journal Science, the group describes how they overcame traditional conflicts arising between tradeoffs involving density and speed to produce an electrode capable of facilitating rapid ion transport   Read More ...
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Secretary of Energy Rick Perry visits Idaho National Laboratory
Secretary of Energy Rick Perry visits Idaho National Laboratory We Matched IDAHO FALLS — Rick Perry made his first trip to the Gem State as the 14th U.S. Secretary of Energy on Monday and Tuesday. The former Texas governor spent the two days touring parts of the Idaho National Laboratory and the Naval Reactors Facility. He was accompanied by U.S. Congressman Mike Simpson, R-Idaho, and Naval Nuclear Propulsion Program Admiral James F   Read More ...
Categories: Politics & Government |  Science & Nature | 
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Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations
Human pluripotent stem cells (hPS cells) can self-renew indefinitely, making them an attractive source for regenerative therapies. This expansion potential has been linked with the acquisition of large copy number variants that provide mutated cells with a growth advantage in culture. The nature, extent and functional effects of other acquired genome sequence mutations in cultured hPS cells are not known. Here we sequence the protein-coding genes (exomes) of 140 independent human embryonic stem cell (hES cell) lines, including 26 lines prepared for potential clinical use   Read More ...
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Multi-phase volcanic resurfacing at Loki Patera on Io
The Jovian moon Io hosts the most powerful persistently active volcano in the Solar System, Loki Patera. The interior of this volcanic, caldera-like feature is composed of a warm, dark floor covering 21,500 square kilometres surrounding a much cooler central ‘island’. The temperature gradient seen across areas of the patera indicates a systematic resurfacing process, which has been seen to occur typically every one to three years since the 1980s   Read More ...
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PhD supervisors: be better mentors
As steering-committee members of the European Association of Students and Post-docs in Synthetic Biology, we find it questionable and unhelpful to blame research students for the breakdown in communication with supervisors (). PhD students today face more challenges than most professors ever did. The supervisor has mentoring responsibilities beyond academic performance, including the student's well-being. Many PhD students crack under the strain of publishing pressures and deteriorating career prospects (see )   Read More ...
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Places: United States | 
The effect of illumination on the formation of metal halide perovskite films
Optimizing the morphology of metal halide perovskite films is an important way to improve the performance of solar cells when these materials are used as light harvesters, because film homogeneity is correlated with photovoltaic performance. Many device architectures and processing techniques have been explored with the aim of achieving high-performance devices, including single-step deposition, sequential deposition and anti-solvent methods. Earlier studies have looked at the influence of reaction conditions on film quality, such as the concentration of the reactants and the reaction temperature   Read More ...
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Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
Wnt proteins modulate cell proliferation and differentiation and the self-renewal of stem cells by inducing β-catenin-dependent signalling through the Wnt receptor frizzled (FZD) and the co-receptors LRP5 and LRP6 to regulate cell fate decisions and the growth and repair of several tissues. The 19 mammalian Wnt proteins are cross-reactive with the 10 FZD receptors, and this has complicated the attribution of distinct biological functions to specific FZD and Wnt subtype interactions   Read More ...
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Brainstorming is not the way to discuss scientific issues
Brainstorming is not the way to discuss scientific issues The idea was simple. Strapped for cash and searching for ways to persuade funders to be more generous, one Italian scientist had a brainwave. Why couldn’t researchers trade their old microscopes for cash? The car company Fiat, after all, ran a scheme that paid owners to relinquish ten-year-old models, with the amount of compensation matched by the government. History suggests the microscope idea went nowhere   Read More ...
Categories: Science & Nature | 
Places: United States | 
Interdisciplinary debate: Agree on definitions of synchrony
Synchronous phenomena are central to many fields, including technology, finance, molecular biology, physics, music and psychology (see Supplementary Information for references). Yet conceptual inconsistencies are thwarting the upsurge of interest in this ubiquitous topic, which a shared definition of synchrony could address. Synchrony is often taken to mean loose coordination patterns among processes, individuals or populations — tidal rhythms and animals' mating behaviours are examples   Read More ...
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Preparation and coherent manipulation of pure quantum states of a single molecular ion
Laser cooling and trapping of atoms and atomic ions has led to advances including the observation of exotic phases of matter, the development of precision sensors and state-of-the-art atomic clocks. The same level of control in molecules could also lead to important developments such as controlled chemical reactions and sensitive probes of fundamental theories, but the vibrational and rotational degrees of freedom in molecules pose a challenge for controlling their quantum mechanical states   Read More ...
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Field Instruments: Build it yourself
Field Instruments: Build it yourself From custom wildlife collars to underwater recorders, a tailor-made field device is within a biologist's grasp. When Lisa O'Bryan was planning her postdoc project in 2014–15, she knew that she couldn't buy field instruments off the shelf. O'Bryan, a behavioural ecologist now at the New Jersey Institute of Technology (NJIT) in Newark, wanted to tag social mammals with audio recorders to investigate how their communication patterns affect the group's activities   Read More ...
Categories: Science & Nature | 
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Core Mediator structure at 3.4 Å extends model of transcription initiation complex
Mediator is a multiprotein co-activator that binds the transcription pre-initiation complex (PIC) and regulates RNA polymerase (Pol) II. The Mediator head and middle modules form the essential core Mediator (cMed), whereas the tail and kinase modules play regulatory roles. The architecture of Mediator and its position on the PIC are known, but atomic details are limited to Mediator subcomplexes. Here we report the crystal structure of the 15-subunit cMed from Schizosaccharomyces pombe at 3   Read More ...
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Decarboxylative alkenylation
Olefin chemistry, through pericyclic reactions, polymerizations, oxidations, or reductions, has an essential role in the manipulation of organic matter. Despite its importance, olefin synthesis still relies largely on chemistry introduced more than three decades ago, with metathesis being the most recent addition. Here we describe a simple method of accessing olefins with any substitution pattern or geometry from one of the most ubiquitous and variegated building blocks of chemistry: alkyl carboxylic acids   Read More ...
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